Toward Personalized Medicine: Using Cardiomyocytes Differentiated From Urine-Derived Pluripotent Stem Cells to Recapitulate Electrophysiological Characteristics of Type 2 Long QT Syndrome

BACKGROUND: Human genetically inherited cardiac diseases have been studied mainly in heterologous systems or animal models, independent of patients’ genetic backgrounds. Because sources of human cardiomyocytes (CMs) are extremely limited, the use of urine samples to generate induced pluripotent stem...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Jouni, Mariam, Si-Tayeb, Karim, Es-Salah-Lamoureux, Zeineb, Latypova, Xenia, Champon, Benoite, Caillaud, Amandine, Rungoat, Anais, Charpentier, Flavien, Loussouarn, Gildas, Baró, Isabelle, Zibara, Kazem, Lemarchand, Patricia, Gaborit, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599503/
https://ncbi.nlm.nih.gov/pubmed/26330336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002159
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