Increased Heme Levels in the Heart Lead to Exacerbated Ischemic Injury

BACKGROUND: Heme is an essential iron-containing molecule for cardiovascular physiology, but in excess it may increase oxidative stress. Failing human hearts have increased heme levels, with upregulation of the rate-limiting enzyme in heme synthesis, δ-aminolevulinic acid synthase 2 (ALAS2), which i...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:J Am Heart Assoc
Autores principales: Sawicki, Konrad Teodor, Shang, Meng, Wu, Rongxue, Chang, Hsiang-Chun, Khechaduri, Arineh, Sato, Tatsuya, Kamide, Christine, Liu, Ting, Naga Prasad, Sathyamangla V, Ardehali, Hossein
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599478/
https://ncbi.nlm.nih.gov/pubmed/26231844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002272
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares