Dual regulation by microRNA-200b-3p and microRNA-200b-5p in the inhibition of epithelial-to-mesenchymal transition in triple-negative breast cancer

Epithelial to mesenchymal transition (EMT) involves loss of an epithelial phenotype and activation of a mesenchymal one. Enhanced expression of genes associated with a mesenchymal transition includes ZEB1/2, TWIST, and FOXC1. miRNAs are known regulators of gene expression and altered miRNA expressio...

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Pubblicato in:Oncotarget
Autori principali: Rhodes, Lyndsay V., Martin, Elizabeth C., Segar, H. Chris, Miller, David F. B., Buechlein, Aaron, Rusch, Douglas B., Nephew, Kenneth P., Burow, Matthew E., Collins-Burow, Bridgette M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599295/
https://ncbi.nlm.nih.gov/pubmed/26062653
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