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MicroRNA-335-5p and -3p Synergize to Inhibit Estrogen Receptor Alpha Expression and Promote Tamoxifen Resistance

microRNAs are small non-coding RNA molecules involved in the regulation of gene expression and play critical roles in human malignancies. Next generation sequencing analysis of the MCF-7 breast cancer cell line overexpressing miR-335-5p and miR-335-3p demonstrated that the miRNA duplex repressed gen...

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Dettagli Bibliografici
Pubblicato in:FEBS Lett
Autori principali: Martin, Elizabeth C., Conger, Adrienne K., Yan, Thomas J., Hoang, Van T., Miller, David F. B., Buechlein, Aaron, Rusch, Douglas B., Nephew, Kenneth P., Collins-Burow, Bridgette M., Burow, Matthew E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5853108/
https://ncbi.nlm.nih.gov/pubmed/28008602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12538
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