ATRX represses alternative lengthening of telomeres

The unlimited proliferation of cancer cells requires a mechanism to prevent telomere shortening. Alternative Lengthening of Telomeres (ALT) is an homologous recombination-mediated mechanism of telomere elongation used in tumors, including osteosarcomas, soft tissue sarcoma subtypes, and glial brain...

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Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Napier, Christine E., Huschtscha, Lily I., Harvey, Adam, Bower, Kylie, Noble, Jane R., Hendrickson, Eric A., Reddel, Roger R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599288/
https://ncbi.nlm.nih.gov/pubmed/26001292
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