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Small molecule inhibition of Axl receptor tyrosine kinase potently suppresses multiple malignant properties of glioma cells

Glioblastoma multiforme (GBM) often features a combination of tumour suppressor gene inactivation and multiple oncogene overactivation. The Axl receptor tyrosine kinase is found overexpressed in GBM and thought to contribute to invasiveness, chemoresistance and poor survival. Here, we have evaluated...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Vouri, Mikaella, An, Qian, Birt, Matthew, Pilkington, Geoffrey J., Hafizi, Sassan
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599264/
https://ncbi.nlm.nih.gov/pubmed/25980499
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