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Axl-EGFR receptor tyrosine kinase hetero-interaction provides EGFR with access to pro-invasive signalling in cancer cells

Acquired resistance to conventional and targeted therapies is becoming a major hindrance in cancer management. It is increasingly clear that cancer cells are able to evolve and rewire canonical signalling pathways to their advantage, thus evading cell death and promoting cell invasion. The Axl recep...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Main Authors: Vouri, M, Croucher, D R, Kennedy, S P, An, Q, Pilkington, G J, Hafizi, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117851/
https://ncbi.nlm.nih.gov/pubmed/27775700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2016.66
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