Ca(2+)/calmodulin-dependent protein kinase IIγ enhances stem-like traits and tumorigenicity of lung cancer cells

Highly tumorigenic stem-like cells, considered tumor-initiating cells (TICs), are the main cause of lung cancer initiation, relapse, and drug resistance. In this study, we identified that Ca(2+)/calmodulin-dependent protein kinase IIγ (CaMKIIγ) was aberrantly expressed in highly tumorigenic stem-lik...

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Pubblicato in:Oncotarget
Autori principali: Chai, Shoujie, Xu, Xia, Wang, Yongfang, Zhou, You, Zhang, Chenchen, Yang, Yiming, Yang, Ying, Xu, Haiyan, Xu, Rongzhen, Wang, Kai
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599257/
https://ncbi.nlm.nih.gov/pubmed/25965829
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