Ca(2+)/calmodulin-dependent protein kinase II-γ (CaMKIIγ) negatively regulates vascular smooth muscle cell proliferation and vascular remodeling

Vascular smooth muscle (VSM) expresses calcium/calmodulin-dependent protein kinase II (CaMKII)-δ and -γ isoforms. CaMKIIδ promotes VSM proliferation and vascular remodeling. We tested CaMKIIγ function in vascular remodeling after injury. CaMKIIγ protein decreased 90% 14 d after balloon injury in rat...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Saddouk, Fatima Z., Sun, Li-Yan, Liu, Yong Feng, Jiang, Miao, Singer, Diane V., Backs, Johannes, Van Riper, Dee, Ginnan, Roman, Schwarz, John J., Singer, Harold A.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2016
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750416/
https://ncbi.nlm.nih.gov/pubmed/26567004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-279158
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