KIF5B-RET fusion kinase promotes cell growth by multilevel activation of STAT3 in lung cancer

BACKGROUND: Lung cancer in nonsmokers tends to be driven by a single somatic mutation or a gene fusion. KIF5B-RET fusion is an oncogene identified in non-small cell lung cancers. In this study, we verified the oncogenic activity of KIF5B-RET fusion and investigated how KIF5B-RET activates the specif...

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Autori principali: Qian, YingYing, Chai, Shoujie, Liang, Zuyu, Wang, Yongfang, Zhou, You, Xu, Xia, Zhang, Chenchen, Zhang, Min, Si, Jingxing, Huang, Feiteng, Huang, Zhangdan, Hong, Wei, Wang, Kai
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4114102/
https://ncbi.nlm.nih.gov/pubmed/25047660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-176
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