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Apatinib inhibits cellular invasion and migration by fusion kinase KIF5B-RET via suppressing RET/Src signaling pathway

The Rearranged during transfection (RET) fusion gene is a newly identified oncogenic mutation in non-small cell lung cancer (NSCLC). The aim of this study is to explore the biological functions of the gene in tumorigenesis and metastasis in RET gene fusion-driven preclinical models. We also investig...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Lin, Chen, Wang, Shanshan, Xie, Weiwei, Zheng, Rongliang, Gan, Yu, Chang, Jianhua
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312308/
https://ncbi.nlm.nih.gov/pubmed/27494860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10985
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