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Dendritic Nanoconjugates for Intracellular Delivery of Neutral Oligonucleotides()
Dendrimer-based gene delivery has been constrained by intrinsic toxicity and suboptimal nanostructure. Conjugation of neutral morpholino oligonucleotides (ONs) with PAMAM dendrimers resulted in neutral, uniform, and ultra-small (~10nm) nanoconjugates. The nanoconjugates dramatically enhanced cellula...
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| 出版年: | Nanoscale |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4598944/ https://ncbi.nlm.nih.gov/pubmed/26134311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5nr01665g |
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