GDF-15 Secreted from Human Umbilical Cord Blood Mesenchymal Stem Cells Delivered Through the Cerebrospinal Fluid Promotes Hippocampal Neurogenesis and Synaptic Activity in an Alzheimer's Disease Model

Our previous studies demonstrated that transplantation of human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) into the hippocampus of a transgenic mouse model of Alzheimer's disease (AD) reduced amyloid-β (Aβ) plaques and enhanced cognitive function through paracrine action. D...

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Detaylı Bibliyografya
Yayımlandı:Stem Cells Dev
Asıl Yazarlar: Kim, Dong Hyun, Lee, Dahm, Chang, Eun Hyuk, Kim, Ji Hyun, Hwang, Jung Won, Kim, Ju-Yeon, Kyung, Jae Won, Kim, Sung Hyun, Oh, Jeong Su, Shim, Sang Mi, Na, Duk Lyul, Oh, Wonil, Chang, Jong Wook
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Mary Ann Liebert, Inc. 2015
Konular:
Original Research Reports
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598918/
https://ncbi.nlm.nih.gov/pubmed/26154268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2014.0487
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