Thrombospondin-1 secreted by human umbilical cord blood-derived mesenchymal stem cells rescues neurons from synaptic dysfunction in Alzheimer’s disease model

Alzheimer’s disease (AD) is an incurable neurodegenerative disease characterised clinically by learning and memory impairments. Amyloid beta (Aβ) peptide-induced synaptic dysfunction is a pathological process associated with early-stage AD. Here, we show that paracrine action of human umbilical cord...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Kim, Dong Hyun, Lim, Hoon, Lee, Dahm, Choi, Soo Jin, Oh, Wonil, Yang, Yoon Sun, Oh, Jeong Su, Hwang, Hyun Ho, Jeon, Hong Bae
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762817/
https://ncbi.nlm.nih.gov/pubmed/29321508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18542-0
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