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A novel combined RNA-protein interaction analysis distinguishes HIV-1 Gag protein binding sites from structural change in the viral RNA leader

RNA-protein interactions govern many viral and host cell processes. Conventional ‘footprinting’ to examine RNA-protein complex formation often cannot distinguish between sites of RNA-protein interaction and sites of RNA structural remodelling. We have developed a novel technique combining photo cros...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kenyon, Julia C., Prestwood, Liam J., Lever, Andrew M. L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598872/
https://ncbi.nlm.nih.gov/pubmed/26449409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14369
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