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In-gel probing of individual RNA conformers within a mixed population reveals a dimerization structural switch in the HIV-1 leader

Definitive secondary structural mapping of RNAs in vitro can be complicated by the presence of more than one structural conformer or multimerization of some of the molecules. Until now, probing a single structure of conformationally flexible RNA molecules has typically relied on introducing stabiliz...

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Bibliografiske detaljer
Main Authors: Kenyon, Julia C., Prestwood, Liam J., Le Grice, Stuart F. J., Lever, Andrew M. L.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794615/
https://ncbi.nlm.nih.gov/pubmed/23935074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt690
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