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In-gel probing of individual RNA conformers within a mixed population reveals a dimerization structural switch in the HIV-1 leader

Definitive secondary structural mapping of RNAs in vitro can be complicated by the presence of more than one structural conformer or multimerization of some of the molecules. Until now, probing a single structure of conformationally flexible RNA molecules has typically relied on introducing stabiliz...

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Detalhes bibliográficos
Main Authors: Kenyon, Julia C., Prestwood, Liam J., Le Grice, Stuart F. J., Lever, Andrew M. L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794615/
https://ncbi.nlm.nih.gov/pubmed/23935074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt690
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