The Contribution of Peroxisome Proliferator-Activated Receptor Alpha to the Relationship Between Toxicokinetics and Toxicodynamics of Trichloroethylene

Exposure to the ubiquitous environmental contaminant trichloroethylene (TCE) is associated with cancer and non-cancer toxicity in both humans and rodents. Peroxisome proliferator-activated receptor-alpha (PPARα) is thought to be playing a role in liver toxicity in rodents through activation of the r...

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書目詳細資料
發表在:Toxicol Sci
Main Authors: Yoo, Hong Sik, Cichocki, Joseph A., Kim, Sungkyoon, Venkatratnam, Abhishek, Iwata, Yasuhiro, Kosyk, Oksana, Bodnar, Wanda, Sweet, Stephen, Knap, Anthony, Wade, Terry, Campbell, Jerry, Clewell, Harvey J., Melnyk, Stepan B., Chiu, Weihsueh A., Rusyn, Ivan
格式: Artigo
語言:Inglês
出版: Oxford University Press 2015
主題:
PPAR-Alpha and TCE Toxicity
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598794/
https://ncbi.nlm.nih.gov/pubmed/26136231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv134
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