The Contribution of Peroxisome Proliferator-Activated Receptor Alpha to the Relationship Between Toxicokinetics and Toxicodynamics of Trichloroethylene

Exposure to the ubiquitous environmental contaminant trichloroethylene (TCE) is associated with cancer and non-cancer toxicity in both humans and rodents. Peroxisome proliferator-activated receptor-alpha (PPARα) is thought to be playing a role in liver toxicity in rodents through activation of the r...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Toxicol Sci
Prif Awduron: Yoo, Hong Sik, Cichocki, Joseph A., Kim, Sungkyoon, Venkatratnam, Abhishek, Iwata, Yasuhiro, Kosyk, Oksana, Bodnar, Wanda, Sweet, Stephen, Knap, Anthony, Wade, Terry, Campbell, Jerry, Clewell, Harvey J., Melnyk, Stepan B., Chiu, Weihsueh A., Rusyn, Ivan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2015
Pynciau:
PPAR-Alpha and TCE Toxicity
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598794/
https://ncbi.nlm.nih.gov/pubmed/26136231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv134
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