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Managing Single-Stranded DNA during Replication Stress in Fission Yeast

Replication fork stalling generates a variety of responses, most of which cause an increase in single-stranded DNA. ssDNA is a primary signal of replication distress that activates cellular checkpoints. It is also a potential source of genome instability and a substrate for mutation and recombinatio...

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Vydáno v:Biomolecules
Hlavní autoři: Sabatinos, Sarah A., Forsburg, Susan L.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598791/
https://ncbi.nlm.nih.gov/pubmed/26393661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom5032123
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