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Targeting the Checkpoint to Kill Cancer Cells

Cancer treatments such as radiotherapy and most of the chemotherapies act by damaging DNA of cancer cells. Upon DNA damage, cells stop proliferation at cell cycle checkpoints, which provides them time for DNA repair. Inhibiting the checkpoint allows entry to mitosis despite the presence of DNA damag...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biomolecules
Prif Awduron: Benada, Jan, Macurek, Libor
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598780/
https://ncbi.nlm.nih.gov/pubmed/26295265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom5031912
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