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Challenges in Antibody Development against Tn and Sialyl-Tn Antigens

The carbohydrate antigens Tn and sialyl-Tn (STn) are expressed in most carcinomas and usually absent in healthy tissues. These antigens have been correlated with cancer progression and poor prognosis, and associated with immunosuppressive microenvironment. Presently they are used in clinical trials...

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Bibliografske podrobnosti
izdano v:Biomolecules
Main Authors: Loureiro, Liliana R., Carrascal, Mylène A., Barbas, Ana, Ramalho, José S., Novo, Carlos, Delannoy, Philippe, Videira, Paula A.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598775/
https://ncbi.nlm.nih.gov/pubmed/26270678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom5031783
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