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Challenges in Antibody Development against Tn and Sialyl-Tn Antigens
The carbohydrate antigens Tn and sialyl-Tn (STn) are expressed in most carcinomas and usually absent in healthy tissues. These antigens have been correlated with cancer progression and poor prognosis, and associated with immunosuppressive microenvironment. Presently they are used in clinical trials...
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| Publicado no: | Biomolecules |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4598775/ https://ncbi.nlm.nih.gov/pubmed/26270678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom5031783 |
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