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The 3' to 5' Exoribonuclease DIS3: From Structure and Mechanisms to Biological Functions and Role in Human Disease

DIS3 is a conserved exoribonuclease and catalytic subunit of the exosome, a protein complex involved in the 3' to 5' degradation and processing of both nuclear and cytoplasmic RNA species. Recently, aberrant expression of DIS3 has been found to be implicated in a range of different cancers...

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Vydáno v:Biomolecules
Hlavní autoři: Robinson, Sophie R., Oliver, Antony W., Chevassut, Timothy J., Newbury, Sarah F.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598762/
https://ncbi.nlm.nih.gov/pubmed/26193331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom5031515
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