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XRN 5’→3’ exoribonucleases: Structure, mechanisms and functions

The XRN family of 5’→3’ exoribonucleases is critical for ensuring the fidelity of cellular RNA turnover in eukaryotes. Highly conserved across species, the family is typically represented by one cytoplasmic enzyme (XRN1/PACMAN or XRN4) and one or more nuclear enzymes (XRN2/RAT1 and XRN3). Cytoplasmi...

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Detalhes bibliográficos
Main Authors: Nagarajan, Vinay K., Jones, Christopher I., Newbury, Sarah F., Green, Pamela J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742305/
https://ncbi.nlm.nih.gov/pubmed/23517755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2013.03.005
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