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Atomic-level characterization of transport cycle thermodynamics in the glycerol-3-phosphate:phosphate antiporter
Membrane transporters actively translocate their substrate by undergoing large-scale structural transitions between inward- (IF) and outward-facing (OF) states (‘alternating-access' mechanism). Despite extensive structural studies, atomic-level mechanistic details of such structural transitions...
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| Publié dans: | Nat Commun |
|---|---|
| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Pub. Group
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4598623/ https://ncbi.nlm.nih.gov/pubmed/26417850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9393 |
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