Hepatic Bmal1 regulates rhythmic mitochondrial dynamics and promotes metabolic fitness

Mitochondria undergo architectural/functional changes in response to metabolic inputs. How this process is regulated in physiological feeding/fasting states remains unclear. Here we show that mitochondrial dynamics (notably fission and mitophagy) and biogenesis are transcriptional targets of the cir...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Jacobi, David, Liu, Sihao, Burkewitz, Kristopher, Kory, Nora, Knudsen, Nelson H., Alexander, Ryan K., Unluturk, Ugur, Li, Xiaobo, Kong, Xiaohui, Hyde, Alexander, Gangl, Matthew R., Mair, William B., Lee, Chih-Hao
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598294/
https://ncbi.nlm.nih.gov/pubmed/26365180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.08.006
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