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Modeling Exon-Specific Bias Distribution Improves the Analysis of RNA-Seq Data

RNA-seq technology has become an important tool for quantifying the gene and transcript expression in transcriptome study. The two major difficulties for the gene and transcript expression quantification are the read mapping ambiguity and the overdispersion of the read distribution along reference s...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Liu, Xuejun, Zhang, Li, Chen, Songcan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598124/
https://ncbi.nlm.nih.gov/pubmed/26448625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140032
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