Temozolomide Resistance in Glioblastoma Cell Lines: Implication of MGMT, MMR, P-Glycoprotein and CD133 Expression

BACKGROUND: The use of temozolomide (TMZ) has improved the prognosis for glioblastoma multiforme patients. However, TMZ resistance may be one of the main reasons why treatment fails. Although this resistance has frequently been linked to the expression of O6-methylguanine-DNA methyltransferase (MGMT...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Perazzoli, Gloria, Prados, Jose, Ortiz, Raul, Caba, Octavio, Cabeza, Laura, Berdasco, Maria, Gónzalez, Beatriz, Melguizo, Consolación
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598115/
https://ncbi.nlm.nih.gov/pubmed/26447477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140131
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky