Sulf1 and Sulf2 Differentially Modulate Heparan Sulfate Proteoglycan Sulfation during Postnatal Cerebellum Development: Evidence for Neuroprotective and Neurite Outgrowth Promoting Functions

INTRODUCTION: Sulf1 and Sulf2 are cell surface sulfatases, which remove specific 6-O-sulfate groups from heparan sulfate (HS) proteoglycans, resulting in modulation of various HS-dependent signaling pathways. Both Sulf1 and Sulf2 knockout mice show impairments in brain development and neurite outgro...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kalus, Ina, Rohn, Susanne, Puvirajesinghe, Tania M., Guimond, Scott E., Eyckerman-Kölln, Pieter J., ten Dam, Gerdy, van Kuppevelt, Toin H., Turnbull, Jeremy E., Dierks, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598108/
https://ncbi.nlm.nih.gov/pubmed/26448642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139853
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados