SRSF1-Regulated Alternative Splicing in Breast Cancer

Splicing factor SRSF1 is upregulated in human breast tumors, and its overexpression promotes transformation of mammary cells. Using RNA-seq, we identified SRSF1-regulated alternative splicing (AS) targets in organotypic three-dimensional MCF-10A cell cultures that mimic a context relevant to breast...

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Vydáno v:Mol Cell
Hlavní autoři: Anczuków, Olga, Akerman, Martin, Cléry, Antoine, Wu, Jie, Shen, Chen, Shirole, Nitin H., Raimer, Amanda, Sun, Shuying, Jensen, Mads A., Hua, Yimin, Allain, Frédéric H.-T., Krainer, Adrian R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597910/
https://ncbi.nlm.nih.gov/pubmed/26431027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.09.005
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