THE SPLICING FACTOR SRSF1 REGULATES APOPTOSIS AND PROLIFERATION TO PROMOTE MAMMARY EPITHELIAL CELL TRANSFORMATION

The splicing-factor oncoprotein SRSF1 (also known as SF2/ASF) is upregulated in breast cancers. We investigated SRSF1’s ability to transform human and mouse mammary epithelial cells in vivo and in vitro. SRSF1-overexpressing COMMA-1D cells formed tumors, following orthotopic transplantation to recon...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Anczuków, Olga, Rosenberg, Avi Z., Akerman, Martin, Das, Shipra, Zhan, Lixing, Karni, Rotem, Muthuswamy, Senthil K., Krainer, Adrian R
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272117/
https://ncbi.nlm.nih.gov/pubmed/22245967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2207
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi