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Splicing-factor oncoprotein SRSF1 stabilizes p53 via RPL5 and induces cellular senescence
Splicing and translation are highly regulated steps of gene expression. Altered expression of proteins involved in these processes can be deleterious. Therefore, the cell has many safeguards against such misregulation. We report that the oncogenic splicing factor SRSF1, which is overexpressed in man...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3628402/ https://ncbi.nlm.nih.gov/pubmed/23478443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.02.001 |
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