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MicroRNA-22 Inhibits Histone Deacetylase 4 to Promote T Helper-17 Cell-Dependent Emphysema
Smoking-related emphysema is a chronic inflammatory disease driven by T helper 17 (T(H)17) cells through molecular mechanisms that remain obscure. Here we have explored the role of microRNA-22 (miR-22) in emphysema. MiR-22 was upregulated in lung myeloid dendritic cells (mDCs) of smokers with emphys...
שמור ב:
| הוצא לאור ב: | Nat Immunol |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4597310/ https://ncbi.nlm.nih.gov/pubmed/26437241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3292 |
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