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KPNB1 mediates PER/CRY nuclear translocation and circadian clock function

Regulated nuclear translocation of the PER/CRY repressor complex is critical for negative feedback regulation of the circadian clock of mammals. However, the precise molecular mechanism is not fully understood. Here, we report that KPNB1, an importin β component of the ncRNA repressor of nuclear fac...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Lee, Yool, Jang, A Reum, Francey, Lauren J, Sehgal, Amita, Hogenesch, John B
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597257/
https://ncbi.nlm.nih.gov/pubmed/26319354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08647
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