Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity

The mechanisms by which melanoma and other cancer cells evade anti-tumor immunity remain incompletely understood. Here, we show that the growth of tumors formed by mutant Braf(V600E) mouse melanoma cells in an immunocompetent host requires their production of prostaglandin E2, which suppresses immun...

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Publicado en:Cell
Main Authors: Zelenay, Santiago, van der Veen, Annemarthe G., Böttcher, Jan P., Snelgrove, Kathryn J., Rogers, Neil, Acton, Sophie E., Chakravarty, Probir, Girotti, Maria Romina, Marais, Richard, Quezada, Sergio A., Sahai, Erik, Reis e Sousa, Caetano
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597191/
https://ncbi.nlm.nih.gov/pubmed/26343581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.08.015
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