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Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity

The mechanisms by which melanoma and other cancer cells evade anti-tumor immunity remain incompletely understood. Here, we show that the growth of tumors formed by mutant Braf(V600E) mouse melanoma cells in an immunocompetent host requires their production of prostaglandin E2, which suppresses immun...

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Pubblicato in:Cell
Autori principali: Zelenay, Santiago, van der Veen, Annemarthe G., Böttcher, Jan P., Snelgrove, Kathryn J., Rogers, Neil, Acton, Sophie E., Chakravarty, Probir, Girotti, Maria Romina, Marais, Richard, Quezada, Sergio A., Sahai, Erik, Reis e Sousa, Caetano
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597191/
https://ncbi.nlm.nih.gov/pubmed/26343581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.08.015
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