The Epoxyeicosatrienoic Acid Pathway Enhances Hepatic Insulin Signaling and is Repressed in Insulin-Resistant Mouse Liver

Although it is widely accepted that ectopic lipid accumulation in the liver is associated with hepatic insulin resistance, the underlying molecular mechanisms have not been well characterized. Here we employed time resolved quantitative proteomic profiling of mice fed a high fat diet to determine wh...

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Publicat a:Mol Cell Proteomics
Autors principals: Schäfer, Alexander, Neschen, Susanne, Kahle, Melanie, Sarioglu, Hakan, Gaisbauer, Tobias, Imhof, Axel, Adamski, Jerzy, Hauck, Stefanie M., Ueffing, Marius
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2015
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597150/
https://ncbi.nlm.nih.gov/pubmed/26070664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M115.049064
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