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Structural Basis of GD2 Ganglioside and Mimetic Peptide Recognition by 14G2a Antibody

Monoclonal antibodies targeting GD2 ganglioside (GD2) have recently been approved for the treatment of high risk neuroblastoma and are extensively evaluated in clinics in other indications. This study illustrates how a therapeutic antibody distinguishes between different types of gangliosides presen...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Horwacik, Irena, Golik, Przemyslaw, Grudnik, Przemyslaw, Kolinski, Michal, Zdzalik, Michal, Rokita, Hanna, Dubin, Grzegorz
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597138/
https://ncbi.nlm.nih.gov/pubmed/26179345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M115.052720
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