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Structural Basis of GD2 Ganglioside and Mimetic Peptide Recognition by 14G2a Antibody

Monoclonal antibodies targeting GD2 ganglioside (GD2) have recently been approved for the treatment of high risk neuroblastoma and are extensively evaluated in clinics in other indications. This study illustrates how a therapeutic antibody distinguishes between different types of gangliosides presen...

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Bibliografske podrobnosti
izdano v:Mol Cell Proteomics
Main Authors: Horwacik, Irena, Golik, Przemyslaw, Grudnik, Przemyslaw, Kolinski, Michal, Zdzalik, Michal, Rokita, Hanna, Dubin, Grzegorz
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597138/
https://ncbi.nlm.nih.gov/pubmed/26179345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M115.052720
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