FoxM1 Promotes Stemness and Radio-Resistance of Glioblastoma by Regulating the Master Stem Cell Regulator Sox2

Glioblastoma (GBM) is the most aggressive and most lethal brain tumor. As current standard therapy consisting of surgery and chemo-irradiation provides limited benefit for GBM patients, novel therapeutic options are urgently required. Forkhead box M1 (FoxM1) transcription factor is an oncogenic regu...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Lee, Yeri, Kim, Kang Ho, Kim, Dong Geon, Cho, Hee Jin, Kim, Yeonghwan, Rheey, Jinguen, Shin, Kayoung, Seo, Yun Jee, Choi, Yeon-Sook, Lee, Jung-Il, Lee, Jeongwu, Joo, Kyeung Min, Nam, Do-Hyun
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596841/
https://ncbi.nlm.nih.gov/pubmed/26444992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137703
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