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FoxM1 Promotes Stemness and Radio-Resistance of Glioblastoma by Regulating the Master Stem Cell Regulator Sox2

Glioblastoma (GBM) is the most aggressive and most lethal brain tumor. As current standard therapy consisting of surgery and chemo-irradiation provides limited benefit for GBM patients, novel therapeutic options are urgently required. Forkhead box M1 (FoxM1) transcription factor is an oncogenic regu...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lee, Yeri, Kim, Kang Ho, Kim, Dong Geon, Cho, Hee Jin, Kim, Yeonghwan, Rheey, Jinguen, Shin, Kayoung, Seo, Yun Jee, Choi, Yeon-Sook, Lee, Jung-Il, Lee, Jeongwu, Joo, Kyeung Min, Nam, Do-Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596841/
https://ncbi.nlm.nih.gov/pubmed/26444992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137703
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