FoxM1 Regulates Mammary Luminal Cell Fate

Elevated expression of FoxM1 in breast cancer correlates with an undifferentiated tumor phenotype and a negative clinical outcome. However, a role for FoxM1 in regulating mammary differentiation was not known. We identify a novel function of FoxM1, the ability to act as a transcriptional repressor,...

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Autori principali: Carr, Janai R., Kiefer, Megan M., Park, Hyun Jung, Li, Jing, Wang, Zebin, Fontanarosa, Joel, DeWaal, Danielle, Kopanja, Dragana, Benevolenskaya, Elizaveta V., Guzman, Grace, Raychaudhuri, Pradip
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401379/
https://ncbi.nlm.nih.gov/pubmed/22813746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.05.005
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