Essential roles of FoxM1 in Ras-induced liver cancer progression and in cancer cells with stem cell features

BACKGROUND & AIMS: Over-expression of FoxM1 correlates with poor prognosis in hepatocellular carcinoma (HCC). Moreover, the Ras-signaling pathway is found to be ubiquitously activated in HCC through epigenetic silencing of the Ras-regulators. We investigated the roles of FoxM1 in Ras-driven HCC,...

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Detalhes bibliográficos
Publicado no:J Hepatol
Main Authors: Kopanja, Dragana, Pandey, Akshay, Kiefer, Megan, Wang, Zebin, Chandan, Neha, Carr, Janai R., Franks, Roberta, Yu, Dae-Yeul, Guzman, Grace, Maker, Ajay, Raychaudhuri, Pradip
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508215/
https://ncbi.nlm.nih.gov/pubmed/25828473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2015.03.023
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