Affinity Inequality among Serum Antibodies That Originate in Lymphoid Germinal Centers

Upon natural infection with pathogens or vaccination, antibodies are produced by a process called affinity maturation. As affinity maturation ensues, average affinity values between an antibody and ligand increase with time. Purified antibodies isolated from serum are invariably heterogeneous with r...

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Bibliographic Details
Published in:PLoS One
Main Authors: Kang, Myungsun, Eisen, Timothy J., Eisen, Ellen A., Chakraborty, Arup K., Eisen, Herman N.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596808/
https://ncbi.nlm.nih.gov/pubmed/26444899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139222
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