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Attenuation of lithium-induced natriuresis and kaliuresis in P2Y(2) receptor knockout mice
Whole body knockout (KO) of the P2Y(2) receptor (P2Y(2)R) results in enhanced vasopressin V2 receptor activity and increased renal Na(+) conservation. We hypothesized that P2Y(2)R KO mice would be less sensitive to lithium-induced natriuresis and kaliuresis due to attenuated downregulation of one or...
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| 出版年: | Am J Physiol Renal Physiol |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Physiological Society
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4596727/ https://ncbi.nlm.nih.gov/pubmed/23739592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00464.2012 |
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