Genetic Deletion of P2Y(2) Receptor Offers Long-Term (5 Months) Protection Against Lithium-Induced Polyuria, Natriuresis, Kaliuresis, and Collecting Duct Remodeling and Cell Proliferation

Chronic lithium administration for the treatment of bipolar disorder leads to nephrogenic diabetes insipidus (NDI), characterized by polyuria, natriuresis, kaliuresis, and collecting duct remodeling and cell proliferation among other features. Previously, using a 2-week lithium-induced NDI model, we...

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Bibliografiska uppgifter
I publikationen:Front Physiol
Huvudupphovsmän: Zhang, Yue, Riquier-Brison, Anne, Liu, Tao, Huang, Yufeng, Carlson, Noel G., Peti-Peterdi, János, Kishore, Bellamkonda K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2018
Ämnen:
Physiology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6304354/
https://ncbi.nlm.nih.gov/pubmed/30618788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.01765
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