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Activation of ENaC by AVP contributes to the urinary concentrating mechanism and dilution of plasma

Arginine vasopressin (AVP) activates the epithelial Na(+) channel (ENaC). The physiological significance of this activation is unknown. The present study tested if activation of ENaC contributes to AVP-sensitive urinary concentration. Consumption of a 3% NaCl solution induced hypernatremia and plasm...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Mironova, Elena, Chen, Yu, Pao, Alan C., Roos, Karl P., Kohan, Donald E., Bugaj, Vladislav, Stockand, James D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596725/
https://ncbi.nlm.nih.gov/pubmed/25391898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00246.2014
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