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Differential polarisation of Csk between naïve and antigen-experienced CD8(+) T cells
In CD8(+) T cells, engagement of the TCR with agonist peptide:MHC molecules causes dynamic redistribution of surface molecules including the CD8 co-receptor to the immunological synapse. CD8 associates with the Src-family kinase Lck, which in turn initiates the rapid tyrosine phosphorylation events...
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| Publicado no: | J Immunol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4595994/ https://ncbi.nlm.nih.gov/pubmed/23427257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202408 |
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