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Memory CD8(+) T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells

The rules that govern memory T cell differentiation are not well understood. This study shows that after antigenic stimulation naïve CD8(+) T cells become committed to dividing at least seven times and differentiating into effector and memory cells. Once the parental naïve CD8(+) T cell had been act...

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Detalhes bibliográficos
Main Authors: Kaech, Susan M., Ahmed, Rafi
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760150/
https://ncbi.nlm.nih.gov/pubmed/11323695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/87720
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