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Local Antigen Encounter Is Essential for Establishing Persistent CD8(+) T-Cell Memory in the CNS

While the brain is considered an immune-privileged site, the CNS may nevertheless be the focus of immune mediated inflammation in the case of infection and certain autoimmune diseases, e.g., multiple sclerosis. As in other tissues, it has been found that acute T-cell infiltration may be followed by...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Schøller, Amalie S., Fonnes, Masja, Nazerai, Loulieta, Christensen, Jan P., Thomsen, Allan R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409353/
https://ncbi.nlm.nih.gov/pubmed/30886617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00351
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